Comprehensive Guide to DTP Vaccination: Diphtheria, Tetanus, and Polio
DTP vaccination protects against three serious diseases: Diphtheria, Tetanus, and Polio. Each of these diseases can have severe complications, including respiratory failure, paralysis, and even death. The DTP vaccine is a crucial part of routine immunisation programs worldwide and is highly effective in preventing these life-threatening infections.
What is DTP?
DTP is a combination vaccine that provides protection against three deadly bacterial and viral infections:
- Diphtheria (D): A bacterial infection that affects the throat and airways, potentially leading to breathing difficulties and heart failure.
- Tetanus (T): A bacterial infection causing muscle stiffness, painful spasms, and nervous system complications.
- Polio (P): A viral disease that attacks the nervous system, leading to paralysis and sometimes death.
DTP is one of the most important vaccines in childhood immunisation programs and is also recommended for adults in certain situations.
Signs and Symptoms of DTP
Symptoms of Diphtheria
Symptoms usually start 2 to 5 days after becoming infected.
Symptoms of diphtheria include:
- a thick grey-white coating that may cover the back of your throat, nose and tongue
- a high temperature (fever)
- sore throat
- swollen glands in your neck
- difficulty breathing and swallowing
In countries with poor hygiene, infection of the skin (cutaneous diphtheria) is more common.
If it’s cutaneous diphtheria, it can cause:
- pus-filled blisters on your legs, feet and hands
- large ulcers surrounded by red, sore-looking skin
Symptoms of Tetanus
The symptoms of tetanus usually start around 4 to 21 days after infection. Most people get symptoms after about 10 days.
The symptoms of tetanus include:
- a stiff jaw (lockjaw), which can make opening your mouth difficult
- painful muscle spasms, often in your back, tummy, arms, legs, hands and feet
- difficulty breathing
- swallowing problems
- a high temperature
- sweating
- a fast heartbeat
- fits (seizures)
Symptoms of Polio
There are three forms of polio:
- Mild Polio (Abortive Polio) – Fever, sore throat, headache, nausea.
- Non-Paralytic Polio – Muscle stiffness, neck pain, fatigue.
- Paralytic Polio – Muscle weakness, loss of reflexes, paralysis, breathing difficulty.
Causes of DTP
Causes of Diphtheria
Diphtheria spreads through:
- Respiratory droplets (coughing or sneezing).
- Direct contact with infected wounds or lesions.
- Sharing contaminated items such as utensils or towels.
Causes of Tetanus
Tetanus bacteria are found in:
- Contaminated soil, dust, and manure
- Rusty nails, wounds, and animal bites
- Unclean surgical instruments
Tetanus does not spread from person to person but enters the body through open wounds, burns, or puncture injuries.
Causes of Polio
Polio spreads through:
- Contaminated food and water (faecal-oral route).
- Direct contact with an infected person.
Treatment for DTP
Treatment of Diphtheria
The main treatments are:
- Antibiotics to kill the diphtheria bacteria
- antitoxin therapy – medicines that stop the effects of the harmful substances (toxins) produced by the bacteria
- thoroughly cleaning any infected wounds if you have diphtheria affecting your skin
- supportive care including oxygen therapy and fluids.
Treatment for Tetanus
- Cleaning the wound – any dirt, soil or dead tissue will be removed
- Tetanus immune globulin (TIG) to neutralise the toxin.
- Antibiotics to kill bacteria.
- Muscle relaxants to ease spasms.
- Ventilator support in severe cases.
Treatment for Polio
There is no cure for polio, but supportive treatments include:
- Physical therapy to prevent muscle atrophy.
- Pain relievers for muscle pain.
- Ventilator support for breathing difficulty.
Prevention of DTP
Prevention of Diphtheria
- Vaccination (DTP or DTaP booster).
- Good hygiene practices such as frequent handwashing.
- Avoiding close contact with infected individuals.
Prevention of Tetanus
- DTP Vaccination provides long-term protection.
- Proper wound care to prevent bacterial entry.
- Immediate medical attention for deep wounds or animal bites.
Prevention of Polio
- DTP Vaccination (Polio component in DTP or separate polio vaccine).
- Good hygiene and sanitation.
- Avoiding contaminated water in endemic regions.
Regions Where DTP is Endemic
Diphtheria Endemic Regions
- Parts of Africa, South America, and Southeast Asia.
Tetanus Endemic Regions
- Tropical and rural areas with poor sanitation.
- High-risk countries include India, Bangladesh, and some African nations.
Polio Endemic Regions
- Afghanistan and Pakistan are the last two countries with wild polio cases.

Why Vaccinate at Trio Pharmacy's Travel & Vaccination Clinic in Shepperton?
If you’re planning to travel to an endemic region or want to protect yourself against DTP, Trio Pharmacy’s Travel & Vaccination Clinic in Shepperton is your trusted destination.
- Expert Guidance: Our trained healthcare professionals provide personalised advice tailored to your needs.
- Convenient Appointments: Flexible booking options to suit your schedule.
- Comprehensive Care: We ensure you receive the most up-to-date vaccinations and travel health information.